The Article was selected by the editors for Spotlight: as an article of Significant Interest. e00902-17
Lipid-accumulating strains of bacteria have considerable potential for the sustainable production of high-value lipids such as wax esters, which are widely used in cosmetics and as lubricants. The lipid biosynthetic capabilities of rhodococci have long been recognized, but many aspects of this synthesis are poorly understood. Round et al. ( e00902-17) identified a key enzyme in wax ester synthesis in rhodococci and exploited it to significantly improve the yield of these molecules. In doing so, this work contributes to the development of novel bioprocesses for an important class of oleochemicals.