Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response. Perona-Wright G, Kohlmeier JE, Bassity E, Freitas TC, Mohrs K, Cookenham T, Situ H, Pearce EJ, Woodland DL, Mohrs M. Source Trudeau Institute, Saranac Lake, NY 12983. Abstract CD8+ T cells are central to the eradication of intracellular pathogens, but they can also act to limit inflammation and immunopathology. During primary respiratory viral infection CD8+ effector T cells release the immunosuppressive cytokine IL-10, which is... Read More
1. Achtman, A.H., S. Pilat, C.W. Law, D.J. Lynn, L. Janot, M. Mayer, S. Ma, J. Kindrachuk, B.B. Finlay, F.S.L. Brinkman, G.K. Smyth, R.E.W. Hancock and L. Schofield. 2012. Effective adjunctive therapy by an innate defense regulatory peptide in a pre-clinical model of severe malaria. Science Transl. Med. 4:135ra64. Severe malaria is a blood borne parasitic disease that afflicts more than 200 million individuals annually. Even in the best clinical settings case fatality rates remain high since anti-malarial drugs are directed against the parasite but do not reduce life-threatening (brain)... Read More
Maya has accepted a Post-Doc position at McGill University working with Dr. Russell Jones examining the role of metabolic control networks within innate and adaptive immunity. Dr. Poffenberger is a recent graduate from Dr. Marc Horwitz lab within the Department of Microbiology and Immunology where she defended her thesis Coxsackievirus-induced Myocarditis: identifying disease mediators.
Congratulations to Zina, a recent Masters graduate from Dr. Michael Gold's lab in the Department of Microbiology and Immunology at UBC. Zinaida has taken a position with Genentech working on tumour re-initiating cells in colorectal cancer in San Francisco, California.
Congratulations to Grace. She has been awarded a Michael G. DeGroote Fellowship from McMaster University. She has begun her postdoc working in Dr. Gerry Wright’s laboratory working on antibiotic resistance.