Seminar - Diversification of Pseudomonas aeruginosa in cystic fibrosis airways
presents a seminar by:
Abstract: The opportunistic bacterial pathogen Pseudomonas aeruginosa causes fatal pulmonary infections in individuals with the genetic disease cystic fibrosis (CF). Phenotypic and genetic diversity are features of P. aeruginosa populations during chronic infection. However, little is known about how this diversity impacts factors such as antimicrobial resistance and patient clinical outcome. Here, I will discuss how we have coupled culture-dependent and -independent methods to characterize a P. aeruginosa population in an adult with CF and identified novel mutations in a key pathoadaptive target involved in antimicrobial resistance.
The Department of Microbiology and Immunology